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Megamindis a 2010 animated comedy film produced by DreamWorks Animation, Red Hour Films and Paramount Pictures. It features the voices of Will Ferrell, Tina Fey, Jonah Hill, David Cross and Brad Pitt. The film is directed by Tom McGrath.

Megamind (Will Ferrell) and his life-long archenemy Metro Man (Brad Pitt) are aliens that were sent away from their respective home planets in time of crisis (much like Superman's origin story), with Metro Man ending up a popular celebrity and Megamind becoming a belittled outcast due to his unintentionally disastrous intellect. Megamind, taking the role of super villain, tries to conquer Metro City in every imaginable way, each attempt a colossal failure thanks to Metro Man, who becomes known as the city's hero. It seems that the pattern will never cease until Megamind seemingly defeats Metro Man during one of his many botched hostage plots involving news reporter Roxanne Ritchi (Tina Fey). Now freed from his rival's shadow, Megamind proceeds to take control of Metro City. Over time, Megamind comes to the realization that he no longer has any purpose in life without an enemy. To appease his depression, he turns Roxanne's lonely cameraman Hal (Jonah Hill) into Metro City's next big superhero, the fiery-headed Tighten. Unfortunately for Megamind, Tighten decides to utilize his new power against humanity as revenge for the lifetime of rejection he has endured. When Metro Man is discovered alive by Megamind and Roxanne, but uninterested in resuming his superhero duties, Megamind is forced to do the inevitable: become the hero of the crisis. Aided by his childhood, fish-like sidekick Minion (David Cross), Megamind sets off to stop Tighten.